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Sedentary Behavior and Cardiovascular Disease Risk: Mediating Mechanisms

Carter, Sophie ORCID: https://orcid.org/0000-0003-2815-7360, Hartman, Yvonne, Holder, Sophie, Thijssen, Dick H.J. and Hopkins, Nicola (2017) Sedentary Behavior and Cardiovascular Disease Risk: Mediating Mechanisms. Exercise and Sport Sciences Reviews, 45 (2). pp. 80-86.

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Sedentary behavior has a strong association with cardiovascular disease (CVD) risk, which may be independent of physical activity. To date, the mechanism(s) that mediate this relationship are poorly understood. We hypothesize that sedentary behavior modifies key hemodynamic, inflammatory, and metabolic processes resulting in impaired arterial health. Subsequently, these vascular impairments directly and indirectly contribute to the development of CVD.

Item Type: Article
Status: Published
DOI: https://doi.org/10.1249/JES.0000000000000106
Subjects: Q Science > QP Physiology
School/Department: School of Science, Technology and Health
URI: https://ray.yorksj.ac.uk/id/eprint/3424

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