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Airway clearance and exercise for people with cystic fibrosis: Balancing longevity with life

Rowbotham, Nicola J. ORCID: https://orcid.org/0000-0003-1105-3645 and Daniels, Tracey E. (2021) Airway clearance and exercise for people with cystic fibrosis: Balancing longevity with life. Pediatric Pulmonology.

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Pedpulm exercise review.pdf - Accepted Version
Restricted to Repository staff only until 21 October 2022.

Abstract

Airway clearance has been an integral part of cystic fibrosis (CF) care for almost as long as CF has been identified as a condition. From diagnosis as a neonate through to end-of-life care, airway clearance is an everyday aspect of life, adding a considerable treatment burden to the lives of people with CF. There are many different techniques used for airway clearance which have evolved over time with an aim to improve effectiveness, support adherence and, more recently, to consider the impact of burden. A popular thought is whether airway clearance could be replaced by exercise. With new precision therapies in the form of CFTR modulators available, the CF landscape is rapidly changing, raising the question of whether certain treatments are needed at all. Depending on factors such as CFTR mutation, age, and pre-existing lung damage before starting a CFTR modulator, individuals with CF may need different levels of intensity and type of maintenance treatment. Precision medicine is likely to lead to the need for increased precision and individualized management around other maintenance therapies such as airway clearance

Item Type: Article
Status: Published
DOI: https://doi.org/10.1002/ppul.25734
Subjects: R Medicine > RM Therapeutics. Pharmacology > RM695 Physical therapy. Occupational therapy
School/Department: School of Science, Technology and Health
URI: http://ray.yorksj.ac.uk/id/eprint/5656

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