Herbert, Dr Katharine

• Research Fellow
• School of Science, Technology & Health

Link to Public Profile

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Upstill-Goddard, Rosie, Dreyer, Stephan B, Rebus, Selma, Pilarsky, Christian, Mukhopadhyay, Debabrata, Lord, Christopher J., Biankin, Andrew V, Froeling, Fieke E.M. and Chang, David K (2024) Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma. bioRxiv. (Submitted)

Cooke, Sean F., Wright, Thomas A., Yan Sin, Yuan, Ling, Jiayue, Kyurkchieva, Elka, Phanthaphol, Nattaporn, Mcskimming, Thomas, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Rebus, Selma, Biankin, Andrew V., Chang, David K., Baillie, George S. and Blair, Connor M. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14 (1).

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Puliyadi, Rathi, Prevo, Remko, Rodriguez-Berriguete, Gonzalo, Ryan, Anderson, Ramadan, Kristijan and Higgins, Geoff S. (2020) Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress. Cell death and differentiation, 28. pp. 1333-1346.

Pokrovska, Tzveta D., Jacobus, Egon J., Puliyadi, Rathi, Prevo, Remko, Frost, Sally, Dyer, Arthur, Baugh, Richard, Rodriguez-Berriguete, Gonzalo, Fisher, Kerry, Granata, Giovanna, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Taverner, William K., Champion, Brian R., Higgins, Geoff S., Seymour, Len W. and Lei-Rossmann, Janet (2020) External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase. Cancers, 12 (4). pp. 1-22.

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Ashton, Thomas M., Prevo, Remko, Pirovano, Giacomo and Higgins, Geoff S. (2018) T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics. Cell Death & Disease, 9 (1089).

Prevo, Remko, Pirovano, Giacomo, Puliyadi, Rathi, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Rodriguez-Berriguete, Gonzalo, O’Docherty, Alice, Greaves, William, McKenna, W. Gillies and Higgins, Geoff S. (2018) CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner. Cell Cycle, 17 (12). pp. 1513-1523.

Pirovano, Giacomo, Ashton, Thomas, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Bryant, Richard J, Verrill, Clare L, Cerundolo, Lucia, Buffa, Francesca M, Prevo, Remko, Harrap, Iona, Ryan, Anderson J, Macaulay, Valentine, McKenna, William G and Higgins, Geoff S (2017) TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy. British Journal of Cancer, 117. pp. 503-512.