Herbert, Dr Katharine

• Research Fellow
• School of Science, Technology & Health

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Article

Cooke, Sean F., Wright, Thomas A., Yan Sin, Yuan, Ling, Jiayue, Kyurkchieva, Elka, Phanthaphol, Nattaporn, Mcskimming, Thomas, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Rebus, Selma, Biankin, Andrew V., Chang, David K., Baillie, George S. and Blair, Connor M. (2024) Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC. Scientific Reports, 14 (1).

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Puliyadi, Rathi, Prevo, Remko, Rodriguez-Berriguete, Gonzalo, Ryan, Anderson, Ramadan, Kristijan and Higgins, Geoff S. (2020) Targeting TOPK sensitises tumour cells to radiation-induced damage by enhancing replication stress. Cell death and differentiation, 28. pp. 1333-1346.

Pokrovska, Tzveta D., Jacobus, Egon J., Puliyadi, Rathi, Prevo, Remko, Frost, Sally, Dyer, Arthur, Baugh, Richard, Rodriguez-Berriguete, Gonzalo, Fisher, Kerry, Granata, Giovanna, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Taverner, William K., Champion, Brian R., Higgins, Geoff S., Seymour, Len W. and Lei-Rossmann, Janet (2020) External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase. Cancers, 12 (4). pp. 1-22.

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Ashton, Thomas M., Prevo, Remko, Pirovano, Giacomo and Higgins, Geoff S. (2018) T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics. Cell Death & Disease, 9 (1089).

Prevo, Remko, Pirovano, Giacomo, Puliyadi, Rathi, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Rodriguez-Berriguete, Gonzalo, O’Docherty, Alice, Greaves, William, McKenna, W. Gillies and Higgins, Geoff S. (2018) CDK1 inhibition sensitizes normal cells to DNA damage in a cell cycle dependent manner. Cell Cycle, 17 (12). pp. 1513-1523.

Pirovano, Giacomo, Ashton, Thomas, Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Bryant, Richard J, Verrill, Clare L, Cerundolo, Lucia, Buffa, Francesca M, Prevo, Remko, Harrap, Iona, Ryan, Anderson J, Macaulay, Valentine, McKenna, William G and Higgins, Geoff S (2017) TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy. British Journal of Cancer, 117. pp. 503-512.

Other

Herbert, Katharine ORCID: https://orcid.org/0000-0001-9437-0253, Upstill-Goddard, Rosie, Dreyer, Stephan B, Rebus, Selma, Pilarsky, Christian, Mukhopadhyay, Debabrata, Lord, Christopher J., Biankin, Andrew V, Froeling, Fieke E.M. and Chang, David K (2024) Sequential ATR and PARP Inhibition Overcomes Acquired DNA Damaging Agent Resistance in Pancreatic Ductal Adenocarcinoma. bioRxiv. (Submitted)